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Gerd Mikus Selected Research

Opioid-Induced Constipation

2/2010Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction: review of efficacy and safety data in the treatment of patients experiencing chronic pain.
1/2009Meeting the challenges of opioid-induced constipation in chronic pain management - a novel approach.

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Gerd Mikus Research Topics

Disease

9Body Weight (Weight, Body)
03/2024 - 12/2004
8Malaria
01/2020 - 12/2004
7Neoplasms (Cancer)
06/2023 - 08/2012
5Breast Neoplasms (Breast Cancer)
03/2024 - 12/2020
5Pain (Aches)
10/2019 - 01/2009
5Drug-Related Side Effects and Adverse Reactions
10/2016 - 08/2006
4Heart Failure
03/2023 - 01/2007
4Falciparum Malaria (Plasmodium falciparum Malaria)
01/2020 - 01/2005
3COVID-19
02/2024 - 06/2020
3Invasive Fungal Infections
10/2023 - 01/2019
3Obesity
01/2020 - 05/2016
3Morbid Obesity
01/2020 - 01/2017
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2018 - 08/2012
3Multiple Myeloma
10/2014 - 08/2007
3Constipation
06/2013 - 01/2009
2Atrial Fibrillation
01/2023 - 10/2017
2Hepatitis B
01/2023 - 01/2016
2Hemorrhage
01/2020 - 01/2011
2Critical Illness (Critically Ill)
02/2019 - 04/2006
2Sarcoma (Soft Tissue Sarcoma)
08/2017 - 01/2016
2Vomiting
10/2014 - 01/2011
2Nausea
10/2014 - 01/2011
2Chronic Pain
02/2010 - 01/2009
2Opioid-Induced Constipation
02/2010 - 01/2009
1Rheumatic Diseases (Rheumatism)
12/2023
1Chronic Disease (Chronic Diseases)
12/2023
1Congenital Heart Defects (Congenital Heart Defect)
01/2023
1Chronic Hepatitis B
01/2023
1Frailty
01/2023
1Venous Thrombosis (Deep-Vein Thrombosis)
01/2023
1Infections
01/2022
1Angina Pectoris
01/2022
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021
1Gastroesophageal Reflux (GERD)
12/2020

Drug/Important Bio-Agent (IBA)

8Voriconazole (Vfend)FDA LinkGeneric
10/2023 - 08/2006
7Methylene Blue (Methylthioninium Chloride)FDA Link
06/2010 - 12/2004
6AnticoagulantsIBA
01/2023 - 06/2008
4Cytochrome P-450 CYP3AIBA
02/2022 - 03/2005
4VaccinesIBA
01/2020 - 08/2012
4Chloroquine (Aralen)FDA LinkGeneric
10/2006 - 12/2004
3Cytochrome P-450 CYP2D6 (CYP2D6)IBA
03/2024 - 05/2021
3TamoxifenFDA LinkGeneric
03/2024 - 02/2021
3Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
12/2023 - 03/2005
3vericiguatIBA
03/2023 - 01/2022
3Proteins (Proteins, Gene)FDA Link
02/2022 - 03/2008
3Fentanyl (Sublimaze)FDA LinkGeneric
10/2019 - 01/2017
3EnzymesIBA
01/2019 - 03/2005
3Analgesics (Analgesic Drugs)IBA
01/2011 - 01/2009
3Naloxone (Narcan)FDA LinkGeneric
02/2010 - 03/2000
3Drug CombinationsIBA
10/2006 - 01/2005
24-hydroxy-N-desmethyltamoxifenIBA
03/2024 - 02/2021
2Ritonavir (Norvir)FDA Link
02/2024 - 12/2023
2Hydroxychloroquine (Plaquenil)FDA LinkGeneric
12/2023 - 06/2020
2Antiviral Agents (Antivirals)IBA
01/2023 - 01/2016
2AnionsIBA
02/2022 - 12/2020
2Ketoconazole (Nizoral)FDA LinkGeneric
02/2022 - 10/2016
2Peptides (Polypeptides)IBA
02/2022 - 12/2020
2Cytochrome P-450 CYP2C19IBA
02/2022 - 08/2006
2Soluble Guanylyl CyclaseIBA
01/2022 - 01/2007
2Cytochrome P-450 CYP3A InhibitorsIBA
01/2021 - 08/2006
2Sufentanil (Sufenta)FDA LinkGeneric
03/2018 - 01/2018
2Alfentanil (Alfenta)FDA LinkGeneric
03/2018 - 01/2018
2VorinostatFDA Link
08/2017 - 01/2016
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2015 - 08/2012
2Aprepitant (Emend)FDA Link
10/2014 - 12/2010
2Melphalan (Alkeran)FDA LinkGeneric
10/2014 - 12/2010
2Antimalarials (Antimalarial Agents)IBA
06/2010 - 03/2008
2Opioid Receptors (Opioid Receptor)IBA
02/2010 - 01/2009
2Oxycodone (Oxycontin)FDA LinkGeneric
02/2010 - 01/2009
2Opioid Analgesics (Opioids)IBA
02/2010 - 01/2009
1Cytochrome P-450 CYP2C9IBA
03/2024
1Hormones (Hormone)IBA
03/2024
1Cytochrome P-450 CYP2D6 InhibitorsIBA
03/2024
1Factor Xa InhibitorsIBA
02/2024
1nirmatrelvir and ritonavir drug combinationIBA
02/2024
1Phosphotransferases (Kinase)IBA
06/2023
1bulevirtideIBA
01/2023
1apixabanIBA
01/2023
1Factor Xa (Coagulation Factor Xa)IBA
01/2023
1nirmatrelvirIBA
01/2022
1NitratesIBA
01/2022
1Nitroglycerin (Dynamite)FDA LinkGeneric
01/2022
1Estrogen ReceptorsIBA
05/2021
1CrizotinibIBA
01/2021
1Anaplastic Lymphoma KinaseIBA
01/2021
1CobicistatIBA
01/2021
1Furosemide (Lasix)FDA LinkGeneric
12/2020
1Digoxin (Digitek)FDA LinkGeneric
12/2020
1Metformin (Glucophage)FDA LinkGeneric
12/2020
1Organic Cation Transporter 2IBA
12/2020
1Rosuvastatin Calcium (Crestor)FDA Link
12/2020
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
12/2020
1Organic Anion TransportersIBA
12/2020
1Pantoprazole (Protonix)FDA LinkGeneric
06/2020

Therapy/Procedure

10Therapeutics
02/2024 - 04/2006
4Drug Therapy (Chemotherapy)
01/2016 - 12/2010
2Palliative Care (Palliative Therapy)
10/2019 - 06/2013
2Bariatric Surgery
06/2017 - 01/2017
2Stem Cell Transplantation
10/2014 - 12/2010
1Polypharmacy
12/2023